I had thought for a while about looking up the current research into HSP/FSP, primarily to see if I could find any stories/studies involving stem cells. It would seem that the Australian HSP group are funding such a study - details of which are here:
Stem Cell Pilot Study 2009/10
What is it?
- Growing and maintaining olfactory stem cell lines
- Differentiating them to other nerve cells and
- Defining biological differences in SPG4 cell lines from normal cell lines.
I also found an earlier study which had looked at them here:
HSP Promotion Award
Reconstitution of neural functions in the spinal cord through neural stem cells expressing the neural cell adhesion molecule L1
I also found another couple of sites giving other research studies into HSP, and have included them here for completeness.
SPG4 Genetic Research Study
HSP Genetic Study
Dr Jamilé HAZAN's team has demonstrated that in the zebrafish atlastin, the protein encoded by the SPG3Agene, controls the architecture of spinal motor neurons and thus the mobility of the larvae during embryonic development of this small fish.